IN-SILICO MOLECULAR MODELLING, MM/GBSA BINDING FREE ENERGY AND MOLECULAR DYNAMICS SIMULATION STUDY OF NOVEL PYRIDO FUSED IMIDAZO[4,5-C]QUINOLINES AS POTENTIAL ANTI-TUMOR AGENTS

In-silico molecular modelling, MM/GBSA binding free energy and molecular dynamics simulation study of novel pyrido fused imidazo[4,5-c]quinolines as potential anti-tumor agents

With an alarming increase in the number of cancer patients and a variety of tumors, it is high time for intensive investigation on more efficient and potent anti-tumor agents.Though numerous agents have enriched the literature, still there exist challenges, with the availability of different targets and possible Spirits cross-reactivity.Herein we h

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Token-Based Access Control

Traditional centralized access control has some shortcomings in robustness, trustworthiness and circulation.Blockchains have the advantages of fault tolerance and trust.Smart contracts have the characteristics of automatic execution and flexible expansion.Tokens can well record credential information and transfer easily.In this UC-II paper, blockch

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